Glyceryl trinitrate cream versus lateral sphincterotomy in management of chronic anal fissure: a prospective randomized comparative study

Comparative study of lateral internal sphincterotomy versus local 0.2% glyceryl trinitrate ointment for the treatment of chronic anal fissure.

The gold standard surgical treatment of chronic anal fissure is lateral internal sphincterotomy which lowers the resting anal pressure and effectively heals the majority of fissures. Local application of 0.2% glyceryl trinitrate ointment has been used as an agent for chemical sphincterotomy, causing temporary alleviation of sphincter spasm and allowing the fissure to heal without compromising t...

Diltiazem (2%) versus glyceryl trinitrate cream (0.2%) in the management of chronic anal fissure.

OBJECTIVE To assess and compare the effectiveness of topical 0.2% glycerl trinitrate (GTN) and topical 2% diltiazem (DTZ), in the management of chronic anal fissure. STUDY DESIGN Comparative, descriptive study. PLACE AND DURATION OF STUDY Department of Surgery, Liaquat University of Medical and Health Sciences, Jamshoro/Hyderabad from September 2004 to August 2005. METHODOLOGY Patients wi...

Topical Diltiazem versus topical Glyceryl trinitrate (GTN) in the treatment of chronic anal fissure: Prospective study

Chronic Anal Fissure; Comparison of Lateral Anal Sphincterotomy (closed Method) versus Anal Dilatation

INTRODUCTION removed/ treated. Mostly, such types of fissures are Anal fissure is a distinct clinicopathological condition of situated eccentrically around the anal margin. the lower anal canal. It can be defined as a longitudinal ulcer in the anoderm usually in the posterior midline, less There is no trace of surgery of anal fissure in literature th frequently in the anterior midline, and rare...

Efficacy and side effects of glyceryl trinitrate in management of chronic anal fissure.

BACKGROUND Various options are available for treatment of chronic anal fissure, each with its own associated complications. This study aimed to evaluate the efficacy of topical Glyceryl Trinitrate (GTN) for anal fissures in an outpatient setting. METHODS A prospective experimental study was carried out at the outpatient department of Surgical Unit IV, Liaquat University Hospital from Aug 2004...